Detalhe da pesquisa
1.
Flotetuzumab and other T-cell immunotherapies upregulate MHC class II expression on acute myeloid leukemia cells.
Blood
; 141(14): 1718-1723, 2023 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36563336
2.
Flotetuzumab as salvage immunotherapy for refractory acute myeloid leukemia.
Blood
; 137(6): 751-762, 2021 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32929488
3.
Targeting CD123 in acute myeloid leukemia using a T-cell-directed dual-affinity retargeting platform.
Blood
; 127(1): 122-31, 2016 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26531164
4.
Application of dual affinity retargeting molecules to achieve optimal redirected T-cell killing of B-cell lymphoma.
Blood
; 117(17): 4542-51, 2011 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21300981
5.
Antitumor activity of the investigational B7-H3 antibody-drug conjugate, vobramitamab duocarmazine, in preclinical models of neuroblastoma.
J Immunother Cancer
; 11(9)2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37775116
6.
Teplizumab for treatment of type 1 diabetes (Protégé study): 1-year results from a randomised, placebo-controlled trial.
Lancet
; 378(9790): 487-97, 2011 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-21719095
7.
Efficacy of Flotetuzumab in Combination with Cytarabine in Patient-Derived Xenograft Models of Pediatric Acute Myeloid Leukemia.
J Clin Med
; 11(5)2022 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35268423
8.
Preclinical Evaluation of IMGC936, a Next-Generation Maytansinoid-based Antibody-drug Conjugate Targeting ADAM9-expressing Tumors.
Mol Cancer Ther
; 21(7): 1047-1059, 2022 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35511740
9.
Dual checkpoint targeting of B7-H3 and PD-1 with enoblituzumab and pembrolizumab in advanced solid tumors: interim results from a multicenter phase I/II trial.
J Immunother Cancer
; 10(4)2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35414591
10.
Anti-tumor activity and toxicokinetics analysis of MGAH22, an anti-HER2 monoclonal antibody with enhanced Fcγ receptor binding properties.
Breast Cancer Res
; 13(6): R123, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-22129105
11.
C-reactive protein inhibits insulin activation of endothelial nitric oxide synthase via the immunoreceptor tyrosine-based inhibition motif of FcgammaRIIB and SHIP-1.
Circ Res
; 104(11): 1275-82, 2009 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-19423845
12.
Therapeutic control of B cell activation via recruitment of Fcgamma receptor IIb (CD32B) inhibitory function with a novel bispecific antibody scaffold.
Arthritis Rheum
; 62(7): 1933-43, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20506263
13.
The inhibitory Fc gamma IIb receptor dampens TLR4-mediated immune responses and is selectively up-regulated on dendritic cells from rheumatoid arthritis patients with quiescent disease.
J Immunol
; 183(7): 4509-20, 2009 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19734236
14.
A humanized CD3ε-knock-in mouse model for pre-clinical testing of anti-human CD3 therapy.
PLoS One
; 16(2): e0245917, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33596227
15.
Efficacy of Margetuximab vs Trastuzumab in Patients With Pretreated ERBB2-Positive Advanced Breast Cancer: A Phase 3 Randomized Clinical Trial.
JAMA Oncol
; 7(4): 573-584, 2021 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33480963
16.
Intramolecular regulation of phospholipase C-gamma1 by its C-terminal Src homology 2 domain.
Mol Cell Biol
; 27(3): 854-63, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17116690
17.
Development and Preliminary Clinical Activity of PD-1-Guided CTLA-4 Blocking Bispecific DART Molecule.
Cell Rep Med
; 1(9): 100163, 2020 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33377134
18.
Preclinical Development of MGC018, a Duocarmycin-based Antibody-drug Conjugate Targeting B7-H3 for Solid Cancer.
Mol Cancer Ther
; 19(11): 2235-2244, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32967924
19.
Fc optimization of therapeutic antibodies enhances their ability to kill tumor cells in vitro and controls tumor expansion in vivo via low-affinity activating Fcgamma receptors.
Cancer Res
; 67(18): 8882-90, 2007 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17875730
20.
CAR T Cells Targeting B7-H3, a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors.
Clin Cancer Res
; 25(8): 2560-2574, 2019 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30655315